No matter how much you know, it's still a very small percentage of the actual knowledge that is present in the cosmos.
The cosmos was here before we came into being and it will be here, after we're gone.
IMO - We humans do not have the capacity to understand what we are or where we are.
Throughout history just when we think we have something figured out, we find that we were completely wrong. This paradigm happens again and again throughout history.
It appears that our ignorance is truly limitless.